Curly Coat Genes
Two Dominant Curly Coat Genes have been isolated, the KRT25 mutation and the SP6 mutation. These gene mutations give Curlies their Curly Coats. Horses with Wild Type KRT25 and Wild Type SP6 do not have have the mutation or the Curly coats and are straight haired. It is the mutations in these two genes that give us our Curly coats in the following lines:
KRT25 mutation is found in the following Curly lines: Damele, Native/Warrior (Eli Bad Warrior, Berndt, Hammrich, NTS), Canadian (Cypress, Sjkonsberg, Naismith), Fredell, WY Salt Wells mustangs and most Nevada mustangs.
SP6 mutation is found in the Curly Jim line- which includes Walker's Prince T, McKay line and Circle B ponies. All horses with the SP6 mutation trace back to Curly Jim, an unknown gaited Curly that showed up in Tennessee.
A huge thank you to Dr Gus Cothran of TX A&M and the French researchers for finding KRT25 and to the German research team for finding SP6. Dr Cothran has confirmed the SP6 gene is found in the Curly Jim line through research testing including the McKay ponies and Circle B ponies.
There are also some unknown Curly coat mutations that have not been identified and that includes some Curly mustangs, the Cook line horses and two curly McKay line ponies out of a SP6 mutation heterozygous sire x straight mares that do not have the SP6 mutation. We have more mysteries to solve and continued research is progressing.
KRT25 mutation is found in the following Curly lines: Damele, Native/Warrior (Eli Bad Warrior, Berndt, Hammrich, NTS), Canadian (Cypress, Sjkonsberg, Naismith), Fredell, WY Salt Wells mustangs and most Nevada mustangs.
SP6 mutation is found in the Curly Jim line- which includes Walker's Prince T, McKay line and Circle B ponies. All horses with the SP6 mutation trace back to Curly Jim, an unknown gaited Curly that showed up in Tennessee.
A huge thank you to Dr Gus Cothran of TX A&M and the French researchers for finding KRT25 and to the German research team for finding SP6. Dr Cothran has confirmed the SP6 gene is found in the Curly Jim line through research testing including the McKay ponies and Circle B ponies.
There are also some unknown Curly coat mutations that have not been identified and that includes some Curly mustangs, the Cook line horses and two curly McKay line ponies out of a SP6 mutation heterozygous sire x straight mares that do not have the SP6 mutation. We have more mysteries to solve and continued research is progressing.
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German Research Paper SP6 link- https://www.nature.com/articles/s41598-018-24865-3
KRT25 mutation and SP6 mutation Typical Crosses- Breeding KRT25 and SP6 mutation genes
Since we now have two genes identified, breeding Curlies and passing on different Curly Coat genes has become interesting. For years the two genes have been bred together because breeders did not how we had more than one dominant gene causing Curly coats. With the Typical KRT25 and SP6 Crosses article, we hope breeding becomes easier by knowing what gene outcomes you may produce with typical crosses.
See the article below by Dr Mitch Wilkinson and Bunny Reveglia.
Since we now have two genes identified, breeding Curlies and passing on different Curly Coat genes has become interesting. For years the two genes have been bred together because breeders did not how we had more than one dominant gene causing Curly coats. With the Typical KRT25 and SP6 Crosses article, we hope breeding becomes easier by knowing what gene outcomes you may produce with typical crosses.
See the article below by Dr Mitch Wilkinson and Bunny Reveglia.
| krt25-sp6_typical_crosses.pdf |
We are now offering Curly Coat Gene testing for KRT25 and SP6 mutations now included in the Genetic DNA Panel- see our home page for details and forms.
NEW~ Excellent video presentation by Dr Mitch Wilkinson and Dr Gus Cothran on Curly Coat gene research. Please watch on YouTube- https://youtu.be/RsHmZAu0jxE
NEW~ Excellent video presentation by Dr Mitch Wilkinson and Dr Gus Cothran on Curly Coat gene research. Please watch on YouTube- https://youtu.be/RsHmZAu0jxE